Basophils absolute

What is basophils absolute and what diseases can it alert us to?

Basophils absolute are a type of white blood cell involved in allergic reactions and inflammation. They usually make up less than 1% of the white blood cells in the blood. When the number of basophil cells in the blood is increased, it is called basophilia. This can be an indication of various diseases, such as:

• Chronic myeloid leukaemia: a form of blood cancer in which too many immature white blood cells are produced.

• Myelofibrosis: A disease in which the bone marrow is replaced by scar tissue and blood formation is impaired.

• Polycythaemia vera: A disease in which too many red blood cells are produced and the blood becomes too thick.

• Allergies: Basophils release histamine, a neurotransmitter responsible for the typical symptoms of an allergic reaction, such as itching, swelling or hives.

• Infections: Basophils can also be elevated in some bacterial or viral infections, especially those that weaken the immune system.

To determine the biomarker basophils absolutely, a blood sample is taken and analysed in the laboratory. The number of basophil cells is given in absolute numbers or as a percentage of the total white blood cells. Normal values can vary depending on the laboratory and the measurement method, but are usually between 0 and 200 cells per microlitre of blood or between 0 and 1% of the white blood cells.

An increase or decrease in basophil cells in the blood can have various causes and should always be discussed with a doctor. An accurate diagnosis requires a careful history, a physical examination and, if necessary, further tests.

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