Interleukin-8 (IL-8) - a cytokine that plays a role in the inflammatory response and regulation of the immune system and is used as a marker for inflammation and infection.
Interleukin-8 (IL-8) is a protein produced by the immune system to fight inflammation. It belongs to a group of molecules called cytokines that enable communication between different cells of the immune system. IL-8 acts as a chemical attractant that lures certain white blood cells known as neutrophils to the site of an infection or injury. There, the neutrophils help destroy the pathogens and promote healing.
IL-8 plays an important role in the body's defence against bacterial and viral infections, but also in regulating inflammatory processes in the body. However, when IL-8 is produced too much or for too long, it can lead to chronic or excessive inflammation that can be harmful to tissues. Some conditions associated with elevated IL-8 levels are asthma, chronic obstructive pulmonary disease (COPD), rheumatoid arthritis, inflammatory bowel disease and cancer.
To measure IL-8 levels in the body, a blood test or tissue sample can be taken. The results can provide information about the degree of inflammation and the risk for certain diseases. Treatment for conditions related to IL-8 can vary depending on the cause and severity. Sometimes, medications that inhibit or block the production or action of IL-8 can be used. In other cases, other strategies can be used to reduce inflammation and improve quality of life.